MEDITWIN brings with each other French science and technologies excellence all around digital twins for the long run of healthcare care

Vélizy-Villacoublay, France – January 24, 2024 – The MEDITWIN consortium was declared on December 11, 2023, in the existence of French President Emmanuel Macron. More specifics were being presented at the PariSanté Campus on December 14 in the presence of French Minister Delegate for Market Roland Lescure. The consortium is made up of seven University Healthcare facility Institutes (IHUs), Nantes College Medical center (CHU), Inria, startups and Dassault Systèmes. MEDITWIN will offer you virtual twins for professional medical observe, serving to to improve the quality of treatment for safer, extra available healthcare for all.

The MEDITWIN project will offer you personalized virtual twins of organs, rate of metabolism and cancer, for superior diagnosis and cure. In specific, MEDITWIN will permit doctors to simulate long term situations for a patient. 

Seven new health care methods will be formulated from the virtual twins, in neurology, cardiology and oncology. This will end result in 7 “digital healthcare goods” that will be deployed on a sovereign industrial cloud platform.

The MEDITWIN venture leverages the skills of planet-class partners in every of the fields covered, all-around the 14 founding members of this consortium: Dassault Systèmes, as the industrial leader of the consortium seven University Hospital Institutes at the highest stage of health care and scientific excellence Nantes University Healthcare facility by way of l’institut du thorax startups inHEART, Codoc, Qairnel and Neurometers and Inria by way of 11 challenge groups concerned in this venture.

Virtual twins have turn out to be an indispensable asset in the aeronautics and mobility industries, exactly where virtualization has enabled substantial progress in terms of security, good quality, ecological footprint and price-efficiency. MEDITWIN builds on the encounter amassed by the companions over several decades in the industry of digital twins for health care, these types of as the Living Heart initiative by Dassault Systèmes (backlink), the Living Brain (hyperlink), as effectively as the actions of the PEPR digital well being software co-directed by Inria and INSERM, for instance.

MEDITWIN will enable the industrialization, clinical validation and standardization of these innovations, so that these systems can be deployed in a standardized way and benefit as several folks as possible. The best specifications of treatment will be incorporated into virtualized experiences designed accessible throughout the world, location a new benchmark for quality in health care and supplying a decisive understanding floor for progress in professional medical science.

The added benefits of digital twins will be assessed for healthcare teams, individuals, and the health care process, notably in phrases of improving upon the efficiency of care, good quality of multidisciplinary selection-making, and effectiveness and security of health-related tactics and interventions.

In observe, the MEDITWIN initiative will be produced over 5 several years, from 2024 to 2029. The partners’ investment in this job will be fiscally supported by the French governing administration as component of the “France 2030” plan.

Partner prices
Bernard Charlès, Chairman of Dassault Systèmes

“Virtual twins have effectively enabled the industrial globe to change alone far more sustainably. Today, this technology is opening up new prospects for health care by revealing the techniques of the human physique – by knowledge and symbolizing the invisible. For 40 a long time, Dassault Systèmes has been a pioneer in virtual twins, and we can use our know-how and know-how to transform healthcare practice. The MEDITWIN community-personal alliance is a major action forward, mobilizing the very best of medication, science and know-how to serve long term healthcare. The virtual twin is presently a reality, and MEDITWIN will enable standardize and disseminate it all over the world to benefit tens of millions of individuals.”

Bruno Sportisse, CEO of Inria
“Building an active digital ecosystem can only make France a European chief in digital health care innovation. In line with their strategic partnership signed in 2021, Inria and Dassault Systèmes are actively collaborating in the industry of virtual twins in health care, with an aligned vision of the problems of sovereignty and the digital transformation of health care. Supported by France 2030, the MEDITWIN task, resulting from bold collaboration involving Dassault Systèmes, Inria and IHU France, demonstrates the dedication of these players to constructing a French market at the forefront of rising health care challenges, all for the reward of people.”

Fabrice André, CEO of IHU PRISM of Gustave Roussy
“The MEDITWIN consortium is in line with PRISM’s eyesight of acquiring most cancers avatars to model biology at the affected person level and tailor customized therapies. PRISM will also advantage from the knowledge of the other IHUs, and will be working intently with them to create interdisciplinary jobs.”

“Combining 7 IHUs, Inria and Dassault Systèmes, MEDITWIN is a exceptional public/private collaboration. This special project opens a new period for scaled and automatic preventive drugs, so vital for clients and immensely charge successful. Ultimately, it presents French physicians and scientists the option of relying on a international sector winner in digital wellness for future clinical research.”

Pr. Didier Mutter, CEO, IHU Strasbourg
“Virtual twins will be vital things in the medicine of the future, as they will enable solutions to be simulated to supply patients with the best achievable effects. MEDITWIN is an extraordinary challenge in conditions of its ambition and the issues to be satisfied. It can be also a premiere for the IHU France alliance, uniting a multidisciplinary biomedical exploration functionality that has no parallel everywhere in the world. For IHU Strasbourg, it will be a impressive catalyst for improving upon the minimally invasive management of metastatic colorectal cancer, in shut collaboration with two of its historic founders, Inria and the College Hospitals of Strasbourg.”

Pr. Michel Paques, IHU FOReSIGHT, head of the ophthalmology 4 section and Director of the Clinical Investigation Center at the 15-20 national hospital
“The integration of the FOReSIGHT IHU into the MEDITWIN consortium will permit the massive-scale development of retinal microcirculation twins, enabling customized detection and monitoring of cerebral and cardiovascular ailments in quantitative phrases. This will be the initially improvement of a quantitative microcirculatory biomarker. The FOReSIGHT IHU has created expertise in ground breaking microvascular imaging employing retinal imaging with adaptive optics, a method in which France is a leader, with the aid of French higher-tech corporations and research institutes. This method, special in the planet, will be strengthened with Dassault Systèmes by way of the development of algorithms primarily based in unique on AI to extract morphometric info from significant retinal surfaces. The integration of these measurements into biomarkers that can be used directly by practitioners represents a big obstacle for the transfer from the study laboratory to the consulting home.”

Pr. Stanislas Lyonnet, CEO of Institut Envision
“Institut Visualize is very pleased to have been one particular of the initiators of the strategic partnership among Dassault Systèmes and Alliance IHU France on digital twins. We are delighted to put our medical and exploration excellence in the area of exceptional ailments at the company of the MEDITWIN task. The initial task, produced with Dassault Systèmes and INRIA, considerations cardiology, with a peri-surgical determination assist method created to greatly minimize the mortality level of newborns struggling from congenital heart disorder (Hypoplastic Still left Heart Syndrome) many thanks to a individualized virtual twin of the cardiovascular procedure. Our second task, designed in partnership with Dassault Systèmes and startup CODOC, issues pediatric neurology, with a resource for handling the Multidisciplinary Board Meeting that uses a virtual twin of people to help medical selection-producing and management of scarce epilepsies, in certain Dravet syndrome. These two tasks provide major alternatives for scientists and medical practitioners, who will be able to visualize, examination, fully grasp, and forecast prior to experimenting on individuals.”

Pr. Alexis Brice, CEO of Paris Brain Institute, IHU ICM
“We are delighted to collaborate carefully with Dassault Systèmes and Inria inside of the IHU Alliance. We goal to framework an ecosystem of innovation in health care from which the drugs of tomorrow will arise. The electronic twin embodies the ambitions of the Institute’s research: to streamline the use of wellbeing information at various scales, to model and forecast the evolution of diseases, to diagnose early, and to build personalized medication on a reliable and responsible basis. In MEDITWIN, Paris Brain Institute will add its know-how in detecting Alzheimer’s sickness, vascular dementia and epilepsy, and in examining info from affected individual cohorts.”

Pr. Stéphane Hatem, CEO of IHU ICAN and Director of the UMR 1166 Study Device on Cardiovascular and Metabolic Diseases
“Virtual twin technological know-how opens up choices for novel precision and preventive medication for cardiometabolic health conditions. Its target is to forecast the individual upcoming risk of creating a cardiovascular disorder, based on specific chance profiles, primarily the genomic signature. Such an ambition requires changing the scale of today’s exploration that will be achieved by the MEDITWIN job led by Dassault Systèmes and with all its partners on board.”

Pr. Bertrand Cariou, Director of l’institut du thorax, CHU de Nantes
“Nantes University Clinic, by means of ‘l’institut du thorax’, in collaboration with Dassault Systèmes engineers, will carry out developments aimed at improving the prediction of cardiovascular accidents, which symbolize the foremost trigger of mortality in industrialized countries. To accomplish this intention, the researchers will use knowledge from the SAFIR cohort, an outcome of the CHOPIN (CHOlesterol Personalized INnovation) nationwide translational study task, on individuals with familial hypercholesterolemia with or without the need of cardiovascular sickness. This pilot study in a incredibly superior-chance cardiovascular population will merge medical, multi-omics and imaging info to make a virtual twin model, which will then be validated in a larger cardiovascular inhabitants.”

Todor Jeliaskov, CEO of inHEART
“At inHEART, we are energized to be aspect of MEDITWIN and on the forefront of the digital well being transformation. Inside MEDITWIN, inHEART will concentrate on the prevention of Sudden Cardiac Demise, which normally takes more than 800,000 life just about every yr. We need to move our health care methods from reacting to acute issues to avoiding issues. Digital systems and Artificial Intelligence are accelerating this process.”

Arthur Delapalme, Co-founder and CEO of CODOC
“The MEDITWIN task has succeeded in bringing together the healthcare skills of several distinctive College Medical center Institutes. In our watch, this multidisciplinary strategy is a fruitful way of accelerating investigate and promptly bringing the added benefits of improvements to individuals. As CODOC, we are quite proud to develop one particular of the seven digital twins of this project.”

Stanley Durrleman, CEO of QAIRNEL
“At Qairnel, we’re proud to be aspect of the MEDITWIN challenge. Our virtual twins simulate the evolution of a patient in the early phases of Alzheimer’s ailment. The challenge will allow us to put these systems into the palms of practitioners, to suggest personalised management schemes and therapeutic methods. This will empower us to respond to a person of the major general public wellness troubles of the 21st century.”

Lionel Naccache, Co-Founder of Neurometers
“Neurometers aims to generalize the healthcare use of the electroencephalogram (EEG) to quantify the cerebral signatures of consciousness and cognition. At first created in healthful subjects and non-communicative individuals, with highly authentic outcomes validated in various scientific publications, we have more not too long ago found out and described that this technique could confirm hugely promising in the discipline of neurodegenerative health conditions that impair cognition, these kinds of as Alzheimer’s sickness. For the very first time, immediate measures of cognitive operating could be integrated into schedule clinical checking of people, complementing neuropsychological tests and measures of cerebral atrophy. This tactic could also make it probable to assess the efficacy of new therapies. Our participation in the MEDITWIN challenge is aimed at bettering the top quality of our algorithms by examining a huge cohort of client EEG recordings in an evolutionary method.”


About France 2030
The France 2030 financial commitment system:

  • Demonstrates a double ambition: sustainably renovate vital sectors of our economy (electricity, automotive, aeronautics or house) as a result of technological innovation, and place France not only as a participant, but also as a chief in the environment of tomorrow. From standard analysis, to the emergence of an strategy to the production of a new item or services, France 2030 supports the entire existence cycle of innovation until finally its industrialization.
  • Is unpublished by its magnitude: €54 billion will be invested to guarantee that our organizations, universities and research businesses are totally thriving in their transitions in these strategic sectors. The obstacle: to allow them to respond competitively to the ecological and attractiveness problems of the coming environment, and to provide out the future champions of our sectors of excellence. France 2030 is defined by two cross-cutting objectives consisting in dedicating 50% of its paying out to the decarbonization of the economic system, and 50% to rising gamers, who are the bearers of innovation with no paying that is unfavorable to the atmosphere (in the feeling of the Do No Major Hurt basic principle).
  • Will be applied collectively: made and deployed in consultation with financial, tutorial, neighborhood and European stakeholders to ascertain their strategic orientations and flagship steps. Job leaders are invited to post their software by using open up, demanding and selective treatments to reward from the aid of the Condition.
  • Is led by the Common Secretariat for Investment decision on behalf of the Key Minister and applied by the French Agency for Ecological Changeover (ADEME), the French National Analysis Company (ANR), Bpifrance and the Banque des Territoires.

Extra facts on: | @SGPI_avenir