Specific Therapeutics presents encouraging medical scenario report facts at Science & Know-how Celebration

OSLO, 28 March 2023: Correct THERAPEUTICS AS ("Exact-Tx", Euronext Advancement: EXTX),
a clinical phase precision wellness firm utilising Acoustic Cluster Therapy
(ACT®) across several therapeutic spots, these days offers data from two patients
with liver metastases of colorectal cancer origin treated with ACT in the
clinical Section I ACTIVATE trial.

The offered radiological success from these two patients recommend an enhanced
reaction to normal of care chemotherapy in the tumours that are exposed to ACT
treatment. This aligns well with the preclinical proof that ACT remedy can
boost the reaction to numerous chemotherapies in distinctive cancer designs.
Centered on the initial medical effects, ACT treatment does not include to the security
or tolerability burden on patients. No adverse events viewed as connected to the
ACT treatment method were being noticed in these two people when ACT was combined with
common of treatment chemotherapy. 

The principal investigator of the ACTIVATE analyze, Prof. Dr. Udai Banerji
responses: "Effects of the Period I examine have presented us numerous insights, most
importantly that the treatment did not reveal any surprising aspect consequences either
on its have or worsen the facet results of chemotherapy in the addressed patients.
The benefits also propose a constructive tumour reaction linked with the ACT
procedure. This trial will established the stage for diversifying the use of this
technological innovation platform to a large array of systemic therapies throughout multiple tumour

So significantly, 7 patients have been enrolled in the examine and encouraging insights
have been attained from these clients.

Precise Therapeutics is now in the course of action of finishing the dose-escalation portion
of the analyze and will thereafter randomise up to 20 patients to two dose levels
of ACT in an enlargement component of the Stage I ACTIVATE trial. 

For much more information, please get in touch with:
Per Walday
CEO Exact Therapeutics
E mail: [email protected]

About Exact-Tx

Correct-Tx is a clinical-phase Norwegian precision health corporation building a
engineering system for focused therapeutic enhancement - Acoustic Cluster
Treatment (ACT®).  ACT® follows a exceptional strategy to ultrasound-mediated, specific
drug enhancement - with the probable to drastically amplify the clinical
utility of a large assortment of therapeutic agents across a multitude of indications
together with within oncology (chemotherapy, immunotherapy), infectious disorders,
and brain diseases. www.correct-tx.com

About the Science & Technological know-how Occasion 28 March 2023

Precise-Tx will keep a Science & Engineering Celebration at 13:00-15:00 CET on 28 March
at the Faros assembly space in the Oslo Science Park.  The executive team, as nicely
as Anders Wold and Sir William Castell, Chair and Nonexecutive Director of the
Board, respectively, will introduce Specific-Tx and the ACT® platform engineering.
Prof. Udai Banerji, Principal Investigator of the ACTIVATE study, will current
medical scenario stories from the analyze. 

About ACT®

o ACT® is a proprietary formulation consisting of microbubbles and microdroplets
that are activated through the software of ultrasound with the consequent
enhance in focused shipping and delivery of a co-administered therapeutic agent. 
o ACT® is supported by a robust and wide preclinical package demonstrating
therapeutic improvement in many oncology types (pancreatic, breast, colon,
prostate) as effectively as blood-mind barrier penetration.
o Original aim of the Enterprise is oncology, however the ACT® system has
opportunity throughout therapeutic parts and merchandise lessons. 

Ahead on the lookout statements
This announcement and any resources dispersed in connection with this
announcement could have specified ahead-hunting statements. By their mother nature,
forward-on the lookout statements require hazard and uncertainty simply because they reflect the
Company's recent expectations and assumptions as to potential events and
conditions that might not demonstrate accurate. A amount of substance factors could
trigger precise final results and developments to differ materially from these expressed
or implied by this forward-searching assertion.

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